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Nikolaj H T Petersen Selected Research

Lu 28-179 (Siramesine)

9/2013Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase.
1/2012Identification of cytoskeleton-associated proteins essential for lysosomal stability and survival of human cancer cells.

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Nikolaj H T Petersen Research Topics

Disease

4Neoplasms (Cancer)
07/2016 - 01/2012
3Type C Niemann-Pick Disease (Niemann Pick Disease, Type C)
06/2021 - 01/2016
3Niemann-Pick Diseases (Niemann Pick Disease)
01/2016 - 01/2010
2Disease Progression
06/2021 - 11/2020
2Sphingolipidoses (Sphingolipidosis)
10/2019 - 01/2016
1Neurodegenerative Diseases (Neurodegenerative Disease)
11/2020
1Atherosclerosis
10/2019
1Neurologic Manifestations (Neurological Manifestations)
12/2018
1Gaucher Disease (Gaucher's Disease)
12/2018
1Prostatic Neoplasms (Prostate Cancer)
07/2016
1Fabry Disease (Fabry's Disease)
01/2016
1Sandhoff Disease (Sandhoff's Disease)
01/2016
1Breast Neoplasms (Breast Cancer)
01/2012
1Inborn Genetic Diseases (Disease, Hereditary)
06/2010
1Disease Resistance
04/2009

Drug/Important Bio-Agent (IBA)

3Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA
09/2013 - 01/2010
3Proteins (Proteins, Gene)FDA Link
08/2012 - 04/2009
2Biomarkers (Surrogate Marker)IBA
06/2021 - 11/2020
2arimoclomolIBA
12/2018 - 01/2016
2SphingomyelinsIBA
01/2016 - 09/2013
2Lu 28-179 (Siramesine)IBA
09/2013 - 01/2012
2AcidsIBA
09/2013 - 06/2010
1LipidsIBA
11/2020
1CholesterolIBA
10/2019
1Glucosylceramidase (Glucocerebrosidase)IBA
12/2018
1EnzymesIBA
12/2018
1Loratadine (Alavert)FDA Link
07/2016
1ebastine (Kestin)IBA
07/2016
1Histamine Antagonists (Antihistamines)IBA
07/2016
1AstemizoleIBA
07/2016
1Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2016
1GlycosphingolipidsIBA
01/2016
1lens epithelium-derived growth factorIBA
08/2012
1Small Interfering RNA (siRNA)IBA
01/2012
1monastrolIBA
01/2012
1neodymium pyrocatechin disulfonate (NPD)IBA
01/2010
1SphingosineIBA
04/2009

Therapy/Procedure

3Therapeutics
12/2018 - 09/2013
1Drug Therapy (Chemotherapy)
07/2016
1Oral Administration
01/2016